| distance | reference number | name | latitude | longitude |
| 220.6 | 2532 | Rhems, Black Mingo Creek, Black River, South Caroli | 33.6033 | -79.4267 |
| 220.8 | 703 | Cuckolds Creek, Combahee River, South Carolina | 32.7133 | -80.695 |
| 221.1 | 127 | Bacon Bridge, Ashley River, South Carolina | 32.9583 | -80.2033 |
| 221.4 | 286 | Bluff Plantation, Combahee River, South Carolina | 32.6833 | -80.7383 |
| 222.5 | 99 | Ashepoo, Ashepoo River, South Carolina | 32.7433 | -80.5567 |
| 222.5 | 3148 | Tulifiny River, I-95 bridge, Broad River, South Car | 32.6017 | -80.9033 |
| 222.6 | 2253 | Pimlico, West Branch, Cooper River, South Carolina | 33.095 | -79.9533 |
| 222.7 | 409 | Canaday Landing, south of, Edisto River, South Caro | 32.8133 | -80.4067 |
| 223.0 | 1413 | Jamestown Bridge, Santee River, South Carolina | 33.305 | -79.6783 |
| 223.6 | 1906 | Mt. Pleasant Plantation, Great Pee Dee River, Black | 33.495 | -79.4617 |
| 224.2 | 1171 | Greggs Landing, Matceba Gardens, Ashley River, Sout | 32.9283 | -80.155 |
| 224.4 | 2115 | Old Rice Mill, West Branch, Cooper River, South Car | 33.0783 | -79.925 |
| 224.4 | 3167 | U.S. 17 Bridge, Combahee River, South Carolina | 32.6517 | -80.6833 |
| 224.7 | 2028 | North Dawson Landing, Broad River, Coosawhatchie Ri | 32.5617 | -80.91 |
| 225.0 | 836 | Dupont, Dean Hall, Cooper River, South Carolina | 33.0583 | -79.9367 |
| 225.1 | 3368 | Winea Plantation, Great Pee Dee River, Black River, | 33.535 | -79.3883 |
| 226.0 | 2765 | Sheldon, Huspa Creek, Whale Branch, Coosaw River, S | 32.5833 | -80.7833 |
| 226.2 | 302 | Bonneau Ferry, East Branch, Cooper River, South Car | 33.0717 | -79.8833 |
| 227.0 | 2539 | Richmond Plantation, East Branch, Cooper River, Sou | 33.0767 | -79.855 |
| 227.1 | 278 | Blessing Plantation, East Branch, Cooper River, Sou | 33.055 | -79.88 |
| 227.1 | 2220 | Penny Creek, south of, Edisto River, South Carolina | 32.715 | -80.4367 |
| 227.4 | 1663 | Lobeco, Whale Branch, Coosaw River, South Carolina | 32.5733 | -80.745 |
| 227.8 | 2486 | Quinby Creek bridge, East Branch, Cooper River, Sou | 33.095 | -79.8083 |
| 227.9 | 1090 | General Dynamics Pier, Cooper River, South Carolina | 33.0083 | -79.9233 |
| 227.9 | 1091 | General Dynamics Pier, Cooper River, South Carolina | 33.0083 | -79.9233 |