| distance | reference number | name | latitude | longitude |
| 45.1 | 1842 | Millside, RR. bridge, Christina River, Delaware | 39.725 | -75.56 |
| 45.3 | 2369 | Port Deposit, Susquehanna River, Maryland | 39.6 | -76.1167 |
| 46.3 | 877 | Edgemoor, Delaware | 39.75 | -75.4933 |
| 46.6 | 520 | Charlestown, Northeast River, Maryland | 39.5667 | -75.9667 |
| 46.8 | 3353 | Wilmington Marine Terminal, Delaware | 39.7183 | -75.52 |
| 47.0 | 1757 | Marcus Hook, Pennsylvania (sub) | 39.8117 | -75.4117 |
| 47.1 | 1756 | Marcus Hook, Pennsylvania | 39.8117 | -75.41 |
| 47.3 | 2109 | Old Frenchtown Wharf, Elk River, Maryland | 39.5667 | -75.85 |
| 48.5 | 1970 | New Castle, Chesapeake and Delaware Canal, Delaware | 39.6567 | -75.5617 |
| 48.8 | 1245 | Havre de Grace, Chesapeake Bay, Maryland | 39.5367 | -76.09 |
| 48.8 | 1246 | Havre de Grace, Maryland | 39.5367 | -76.09 |
| 48.8 | 2632 | Salem Canal entrance, Delaware River, New Jersey | 39.6833 | -75.51 |
| 49.4 | 2212 | Pedricktown, Oldmans Creek, New Jersey | 39.7617 | -75.4033 |
| 49.6 | 3255 | Wanamaker Bridge, Darby Creek, Pennsylvania | 39.8767 | -75.305 |
| 49.7 | 342 | Bridgeport, Raccoon Creek, New Jersey, Delaware Riv | 39.8067 | -75.355 |
| 50.0 | 2994 | Summit Bridge, Chesapeake and Delaware Canal, Delaw | 39.55 | -75.7333 |
| 50.0 | 662 | Courthouse Point, Maryland | 39.5167 | -75.8833 |
| 50.1 | 542 | Chesapeake City, Chesapeake and Delaware Canal, Mar | 39.5267 | -75.81 |
| 50.1 | 543 | Chesapeake City, Maryland | 39.5267 | -75.81 |
| 50.2 | 2058 | Norwood City, Darby Creek, Pennsylvania | 39.88 | -75.29 |
| 50.6 | 2119 | Old Town Point Wharf, Maryland | 39.5033 | -75.9167 |
| 50.9 | 3098 | Tinicum National Wildlife Refuge, Darby Creek, Penn | 39.8783 | -75.2767 |
| 51.0 | 991 | Fishing Battery Light, Susquehanna River, Maryland | 39.5 | -76.0833 |
| 51.2 | 3099 | Tinicum National Wildlife Refuge, Darby Creek, Penn | 39.8867 | -75.265 |
| 51.5 | 2915 | St. Georges, Chesapeake and Delaware Canal, Delawar | 39.555 | -75.6483 |